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Background: The effect of perceived risk and work stress on burnout in health workers. Hoax news about the development of the Covid virus affects the perceived risk of health workers. The rapid transmission of covid virus, the increasing number of hospitalizations in all hospitals, full beds, health workers feel work stress and even burnout. Hectic working hours, excessive workload, plus exposed health workers are contributing factors. The purpose of this study is to analyze the effect of perceived risk and work stress on burnout with work motivation as an intervening variable for health workers during the Covid-19 pandemic.

Research Methods: The research method is a quantitative associative cross-sectional design. The type of data used is quantitative data. The population in this study used 50 health workers.

Results: It was found that high perceived risk decreased burnout, high work stress increased burnout. High perceived risk increases work motivation, high work stress reduces work motivation.

Implications: It needs support from hospital management and the government to be able to provide valid information about the development of the covid virus, setting work hours and workloads, providing volunteers if needed, providing schedules incentives, and fulfilling the completeness of infrastructure for personal protective equipment and space inpatient isolation.

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